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From development to degeneration and regeneration of the nervous system

From development to degeneration and regeneration of the nervous system
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Field name Details
Dewey Class 612.82 (DDC 22)
Title From development to degeneration and regeneration of the nervous system (EB) / edited by Charles E. Ribak ... [et al.].
Added Personal Name Ribak, Charles E.
Other name(s) Oxford Scholarship Online
Publication New York ; Oxford : Oxford University Press , 2009
Physical Details 1 online resource
ISBN 9780199865253
Note Published to Oxford Scholarship Online: May 2009 ; Print publication date: 2008
Summary Note This book describes current information about the three areas mentioned in the title: neuronal migration and development, degenerative brain diseases, and neural plasticity and regeneration. The chapters in the first section of the book examine the cellular and molecular mechanisms by which neurons are generated from the ventricular zone in the forebrain and migrate to their destinations in the cerebral cortex. This description of cortical development also includes discussions of the Cajal-Retzius cell. Another chapter provides insight about the development of another forebrain region, the hypothalamus. The remaining chapters of the first section examine the clinical relevance of brain development in certain disease states in humans. The second section begins with details about the dopaminergic neurons in the substantia niger and their loss in Parkinson's disease. Two subsequent chapters describe changes in brain aging, including changes in the numbers of myelinated axons. Other chapters in this section describe important cellular and molecular changes found in Alzheimer's disease and human epilepsy. The last section begins with a chapter on how the brain's own stem cells provide newly generated neurons to the hippocampal dentate gyrus and how these neurons become integrated into neural circuitry. Then two chapters examine some of the neuroplastic changes that take place in motor and sensory cortices of awake behaving primates. The concluding two chapters address the issue of regeneration in the injured spinal cord and the factors that may contribute to its success.:
Mode of acces to digital resource Digital book. - Oxford : Oxford University Press, 2009. - Mode of access: World Wide Web. System requirements: Internet Explorer 6.0 (or higher) or Firefox 2.0 (or higher). Available as searchable text in HTML format.
System details note Online access to this digital book is restricted to subscribing institutions through IP address (only for SISSA internal users)
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